By Shoib Ahmad Baba, Nasheeman Ashraf
This booklet is a fabricated from years of analysis on saffron biology. It intends to provide a extensive yet concise review of a few of the points of apocarotenoid biosynthesis in Crocus sativus, its law and pharmacology .
Crocus sativusL. of family members Iridaceae is a vital medicinal plant. The dried stigma of C. sativus flower is taken into account because the world's most expensive spice. Saffron is the resources of specific carotenoid derived molecules referred to as apocarotenoids which come with crocin, crocetin, picrocrocin and safranal. those molecules are synthesized within the tissue and developmental degree particular demeanour. in addition to delivering color, aroma and flavour to the spice, those molecules have great medicinal value.
The booklet uncovers significant innovations of apocarotenoids biosynthesis and gives deeper and extra entire realizing approximately their biotechnological and pharmacological applications.
The booklet is split into 3 sections –
The first part presents a basic advent of C. sativus, its apocarotenoids, their biosynthesis, legislation and delivery. moment part presents information regarding the carotenoid cleavage dioxygenases (CCDs) that are the most important gamers in apocarotenoid biosynthesis. The type of plant CCDs, their constitution, response mechanism, biotechnological program are completely mentioned. the ultimate part offers with the most important pharmacological homes of C. sativus apocarotenoids, starting from their function as anticancer to their application as neuroprotective molecules.
This is a one in all its variety booklet on Crocus sativus. It might be valuable for the researchers operating on Crocus sativus, students and in addition practitioners fascinated with extraction and bio-synthesis of the valuable clinical components.
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Additional info for Apocarotenoids of Crocus sativus L: From biosynthesis to pharmacology
Sativus stigma, three apocarotenoids crocin, picrocrocin, and safranal accumulate in significant amounts (Baba et al. 2015b). These apocarotenoids are responsible for the color, flavor, and aroma of saffron, making it one of the world’s costliest spice (Rubio et al. 2008; Baba et al. 2015a). Crocins present in C. sativus are powerful free radical quenchers and have been used in traditional medicine since thousands of years. They display a variety of health benefits and have gained attention due to their sedative, analgesic, and anticancer properties (Zhang et al.
I. Picrocrocin. Helv Chimica Acta 5:376–400 Yang B, Guo Z, Liu R (2005) Crocin synthesis mechanism in Crocus sativus. Tsinghua Sci Technol 10(5):567–572 Yazaki K (2005) Transporters of secondary metabolites. Curr Opin Plant Biol 8(3):301–307 Yu F et al (2007) Variegation mutants and mechanisms of chloroplast biogenesis. Plant Cell Environ 30:350–365 Chapter 2 Carotenoid Cleavage Dioxygenases of Crocus sativus L. Abstract Carotenoid cleavage dioxygenases (CCDs) form a multienzyme family, the members of which are involved in the production of a diversity of apocarotenoids.
Engineering carotenoid degradation pathway and will open up opportunities for enhancing plant defense through biotechnological interventions. 2 Color, Flavor, and Aroma Compounds Carotenoids and their cleavage products are involved in the development of aroma and flower color and can be undoubtedly exploited by metabolic engineering. The color of the flower has been modified in many plants including petunia (Van Der Krol et al. 1990), rose (Gutterson 1995), gerbera (Elomaa et al. 1993), carnation (Zuker et al.