By Leopold G. Koss and Dulcie V. Coleman (Auth.)
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R. and SCULLY, R. E. (1977) Precancerous lesions of the endometrium, Human Pathology, 8, 503-512 4 7 . HUGHES, E. C , CSERMELY, T. , JACOBS, R. D. A. (1974) 48. 49. 50. 51. 52. 53. Biochemical parameters of abnormal endometrium, Gynecologic Oncology, 2, 205-220 LEGOASCONGNE, c. and BEAULIEU, E. E. (1977) Hormonally controlled 'nuclear bodies' during the development of the prepuberal rat uterus, Biologie Cellulaire, 30, 195-198 FERENCZY, A. (1979) Recent advances in endometrial neoplasia, Experimental Molecular Pathology, 31, 226-235 GAVASTO, F.
The consistency of diagnosis and an agreement between cytologists and histopathologists of the meaning of the terms used is probably more important that the actual words. A more detailed description of the lesions represented in the Table are provided below. Cystic hyperplasia This may be regarded as an exaggeration or continuation of the normal proliferative phase, so that both glands and stroma usually contribute to the hyperplasia1013. 1 Endometrial hyperplasias Cystic hyperplasia: mild moderate severe Adenomatous hyperplasia 1.
Morse 51 features of adenomatous hyperplasia but, in addition, show atypia of architectural or cellular pattern, or both48. The features of the former include irregularity of the glands, intraglandular bridges and tufting of the epithelium. Cellular atypia includes variation in nuclear size and shape and loss of polarity. Atypical hyperplasia is thus a variant of adenomatous hyperplasia; atypia is usually seen only in the more severe forms of adenomatous hyperplasia although it may sometimes be seen in less severe forms.